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Severe Epileptic Encephalopathies in Children: West and Lennox-Gestaut Syndromes
Gyrus, 3 (2015), 1; 92-96. https://doi.org/10.17486/gyr.3.1022
Šijan, Ivona; Božić, Ivana; Milić, Jakov

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Šijan, I., Božić, I. & Milić, J. (2015). Severe Epileptic Encephalopathies in Children: West and Lennox-Gestaut Syndromes. Gyrus, 3. (1), 92-96. doi: 10.17486/gyr.3.1022

Šijan, Ivona, et al. "Severe Epileptic Encephalopathies in Children: West and Lennox-Gestaut Syndromes." Gyrus, vol. 3, no. 1, 2015, pp. 92-96. https://doi.org/10.17486/gyr.3.1022

Šijan, Ivona, Ivana Božić and Jakov Milić. "Severe Epileptic Encephalopathies in Children: West and Lennox-Gestaut Syndromes." Gyrus 3, no. 1 (2015): 92-96. https://doi.org/10.17486/gyr.3.1022

Šijan, I., Božić, I. and Milić, J. (2015) 'Severe Epileptic Encephalopathies in Children: West and Lennox-Gestaut Syndromes', Gyrus, 3(1), pp. 92-96. doi: 10.17486/gyr.3.1022

Šijan I, Božić I, Milić J. Severe Epileptic Encephalopathies in Children: West and Lennox-Gestaut Syndromes. Gyrus [Internet]. 2015 [cited 2024 April 16];3(1):92-96. doi: 10.17486/gyr.3.1022

I. Šijan, I. Božić and J. Milić, "Severe Epileptic Encephalopathies in Children: West and Lennox-Gestaut Syndromes", Gyrus, vol. 3, no. 1, pp. 92-96, 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:022523. [Accessed: 16 April 2024]

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Metadata
Title (english)Severe Epileptic Encephalopathies in Children: West and Lennox-Gestaut Syndromes
Title (croatian)Teške epileptične encefalopatije u dječjoj dobi: Sindromi West i Lennox – Gastaut
AuthorIvona Šijan
AuthorIvana Božić
AuthorJakov Milić
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Abstract (english)
Epileptic encephalopathies are epilepsy syndromes in which the epileptiform abnormalities themselves are believed to contribute to a progressive disturbance in cerebral function. The two most important syndromes in this group are West and Lennox–Gastaut syndromes. West syndrome frequently occurs in the fi rst year of life, in clusters with consequences such as developmental arrest and mental retardation. It characteristically presents with the triad of infantile epileptic spasms, developmental delay and hypsarrhytmia. The treatment is ACTH, prednisolone or valproate. Lennox–Gastaut syndrome typically presents with multiple seizure types, slow spike–wave complexes in the EEG and impaired cognitive function. It is treated with felbamate, lamotrigine, topiramate and rufi namide with poor response to treatment.
Abstract (croatian)
Epileptične su encefalopatije epileptični sindromi kod kojih se vjeruje da su same epileptiformne abnormalnosti čimbenik nastanka progresivnih poteškoća u cerebralnoj funkciji. Dva najznačajnija sindroma u ovoj skupini su sindromi West i Lennox– Gastaut. Westov sindrom se učestalo pojavljuje u prvoj godini života s posljedicama kao što su zastoj u razvoju i mentalna retardacija. Trijas karakterističan za ovaj sindrom čine infantilni epileptični spazmi, zastoj u razvoju i hipsaritmija. Uobičajeno se liječi s ACTH, prednizolonom ili valproatom. Za Lennox-Gastautov su sindrom tipični različiti oblici konvulzija, spori šiljak-val kompleksi u EEG-u i oštećena kognitivna funkcija. Liječi se felbamatom, lamotriginom, topiramatom i rufi namidom uz slab odgovor na liječenje.
Keywords (english)
Keywords (croatian)
Languageenglish
Publication typeProfessional paper - Professional paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleGyrus
Numberingvol. 3, no. 1, pp. 92-96
p-ISSN2459-5233
e-ISSN1849-5427
DOIhttps://doi.org/10.17486/gyr.3.1022
URN:NBNurn:nbn:hr:239:022523
Publication2015
Document URLhttps://www.researchgate.net/publication/279196496_Severe_Epileptic_Encephalopathies_in_Children_West_and_Lennox-Gestaut_Syndromes
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-01-22 12:44:33