prikaz prve stranice dokumenta Diagnostic Accuracy of a Pocket Screening Spirometer in Diagnosing Chronic Obstructive Pulmonary Disease in General Practice: a Cross Sectional Validation Study Using Tertiary care as a Reference
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Scientific paper - Original scientific paper
Diagnostic Accuracy of a Pocket Screening Spirometer in Diagnosing Chronic Obstructive Pulmonary Disease in General Practice: a Cross Sectional Validation Study Using Tertiary care as a Reference
BMC Family Practice, 17 (2016), 1; 1-11. https://doi.org/10.1186/s12875-016-0518-8
Labor, Marina; Vrbica, Žarko; Gudelj, Ivan; Labor, Slavica; Plavec, Davor

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Labor, M., Vrbica, Ž., Gudelj, I., Labor, S. & Plavec, D. (2016). Diagnostic Accuracy of a Pocket Screening Spirometer in Diagnosing Chronic Obstructive Pulmonary Disease in General Practice: a Cross Sectional Validation Study Using Tertiary care as a Reference. BMC Family Practice, 17. (1), 1-11. doi: 10.1186/s12875-016-0518-8

Labor, Marina, et al. "Diagnostic Accuracy of a Pocket Screening Spirometer in Diagnosing Chronic Obstructive Pulmonary Disease in General Practice: a Cross Sectional Validation Study Using Tertiary care as a Reference." BMC Family Practice, vol. 17, no. 1, 2016, pp. 1-11. https://doi.org/10.1186/s12875-016-0518-8

Labor, Marina, Žarko Vrbica, Ivan Gudelj, Slavica Labor and Davor Plavec. "Diagnostic Accuracy of a Pocket Screening Spirometer in Diagnosing Chronic Obstructive Pulmonary Disease in General Practice: a Cross Sectional Validation Study Using Tertiary care as a Reference." BMC Family Practice 17, no. 1 (2016): 1-11. https://doi.org/10.1186/s12875-016-0518-8

Labor, M., et al. (2016) 'Diagnostic Accuracy of a Pocket Screening Spirometer in Diagnosing Chronic Obstructive Pulmonary Disease in General Practice: a Cross Sectional Validation Study Using Tertiary care as a Reference', BMC Family Practice, 17(1), pp. 1-11. doi: 10.1186/s12875-016-0518-8

Labor M, Vrbica Ž, Gudelj I, Labor S, Plavec D. Diagnostic Accuracy of a Pocket Screening Spirometer in Diagnosing Chronic Obstructive Pulmonary Disease in General Practice: a Cross Sectional Validation Study Using Tertiary care as a Reference. BMC Family Practice [Internet]. 2016 [cited 2024 October 30];17(1):1-11. doi: 10.1186/s12875-016-0518-8

M. Labor, Ž. Vrbica, I. Gudelj, S. Labor and D. Plavec, "Diagnostic Accuracy of a Pocket Screening Spirometer in Diagnosing Chronic Obstructive Pulmonary Disease in General Practice: a Cross Sectional Validation Study Using Tertiary care as a Reference", BMC Family Practice, vol. 17, no. 1, pp. 1-11, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:759079. [Accessed: 30 October 2024]

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Metadata
Title (english)Diagnostic Accuracy of a Pocket Screening Spirometer in Diagnosing Chronic Obstructive Pulmonary Disease in General Practice: a Cross Sectional Validation Study Using Tertiary care as a Reference
AuthorMarina Labor
MBZ: 357633
AuthorŽarko Vrbica
MBZ: 259013
AuthorIvan Gudelj
AuthorSlavica Labor
MBZ: 330076
AuthorDavor Plavec
MBZ: 159962
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
BACKGROUND: COPD-6™ is a lung function testing device for a rapid pre-spirometry testing to screen-out at-risk individuals not having COPD and indicating those at risk. The aim of this study was to validate COPD-6™ lung function testing (index test) in general practice in discriminating patients with COPD out of the population at risk - smokers/ex-smokers with no previous diagnosis of COPD, using measurements at tertiary care as reference standard. METHODS: Consecutive 227 subjects (115 women, 185 smokers/42 ex-smokers, ≥20 pack-years) with no previous diagnosis of COPD, aged 52.5 (SD 6.8) years from 26 general practitioners (GPs) were recruited, lung function tested with COPD-6™, referred to the tertiary institution for repeated COPD-6™ testing followed by spirometry with a bronchodilator (salbutamol), examination, and pulmonologist consultation for the diagnosis and severity of COPD. RESULTS: COPD was diagnosed in 43 subjects (18.9 %), with an AUC of 0.827 (95 % CI 0.769-0.875, P < 0.001) for the diagnosis of COPD when lung function was measured using COPD-6™ in GP's office with a specificity of 100 % (95 % CI, 97.95-100 %) but a very low sensitivity of 32.56 % (95 % CI, 20.49-47.48 %). Significant agreement for forced expiratory volume in 1 s measured at GP's office and at lung function lab was found (mean difference 0.01 L, p = 0.667) but not for other measured parameters (p < 0.001 for all). CONCLUSIONS: Our study results point out that active case finding in a population at risk for COPD should be instituted (almost 20 % of undiagnosed COPD). Based on our results lung function testing with COPD-6™ can substitute spirometry testing in cases where it is not readily available to the patient/physician taken into account that the traditional FEV1/FEV6 cutoff value of <0.7 is not the only criterion for diagnosis and/or further referral.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleBMC Family Practice
Numberingvol. 17, no. 1, pp. 1-11
e-ISSN1471-2296
DOIhttps://doi.org/10.1186/s12875-016-0518-8
URN:NBNurn:nbn:hr:239:759079
Publication2016
Document URLhttps://bmcfampract.biomedcentral.com/articles/10.1186/s12875-016-0518-8
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2019-10-29 13:09:08