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Scientific paper - Review paper
Potentially Inappropriate Medications in the Elderly: a Comprehensive Protocol
European journal of clinical pharmacology, 68 (2012), 8; 1123-38. https://doi.org/10.1007/s00228-012-1238-1
Mimica Matanović, Suzana; Vlahović-Palčevski, Vera

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Mimica Matanović, S. & Vlahović Palčevski, V. (2012). Potentially Inappropriate Medications in the Elderly: a Comprehensive Protocol. European journal of clinical pharmacology, 68. (8), 1123-38. doi: 10.1007/s00228-012-1238-1

Mimica Matanović, Suzana and Vera Vlahović Palčevski. "Potentially Inappropriate Medications in the Elderly: a Comprehensive Protocol." European journal of clinical pharmacology, vol. 68, no. 8, 2012, pp. 1123-38. https://doi.org/10.1007/s00228-012-1238-1

Mimica Matanović, Suzana and Vera Vlahović Palčevski. "Potentially Inappropriate Medications in the Elderly: a Comprehensive Protocol." European journal of clinical pharmacology 68, no. 8 (2012): 1123-38. https://doi.org/10.1007/s00228-012-1238-1

Mimica Matanović, S. and Vlahović Palčevski, V. (2012) 'Potentially Inappropriate Medications in the Elderly: a Comprehensive Protocol', European journal of clinical pharmacology, 68(8), pp. 1123-38. doi: 10.1007/s00228-012-1238-1

Mimica Matanović S, Vlahović Palčevski V. Potentially Inappropriate Medications in the Elderly: a Comprehensive Protocol. European journal of clinical pharmacology [Internet]. 2012 [cited 2024 November 16];68(8):1123-38. doi: 10.1007/s00228-012-1238-1

S. Mimica Matanović and V. Vlahović Palčevski, "Potentially Inappropriate Medications in the Elderly: a Comprehensive Protocol", European journal of clinical pharmacology, vol. 68, no. 8, pp. 1123-38, 2012. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:699288. [Accessed: 16 November 2024]

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Metadata
Title (english)Potentially Inappropriate Medications in the Elderly: a Comprehensive Protocol
AuthorSuzana Mimica Matanović
MBZ: 292855
AuthorVera Vlahović-Palčevski
MBZ: 194575
Author's institution(Clinical hospital center Osijek)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Abstract (english)
Elderlypatients areatincreasedriskofdrug-related morbidity and mortality. Avoiding the use of potentially inappropriate medications (PIMs) is one of the strategies that has been widely adopted to reduce the harmful consequences of drug use. There are several PIM screening tools available. In thisreview,weprovideanoverviewofexistingscreeningtools to detect PIMs in the elderly, emphasizing the advantages and disadvantages of each. Combining previously published and adopted tools (adjusted Beers list, French consensus panel, McLeod’s list, and Lindblad’s list of clinically important drug–disease interactions), we develop a new comprehensive toolthatalsoincludestheadjustedHanlon’sandMalone ’slists of potentially serious drug–drug interactions in the elderly. In addition to listed PIMs and clinically important drug–drug interactions, alternative therapeutic solutions are suggested. The new protocol differentiates: drugs with an unfavorable benefit/risk ratio (to be avoided regardless of the underlying disease/condition), drugs with a questionable efficacy, and drugs to be avoided with certain diseases/conditions, and providesalistofpotentiallyseriousdrug–druginteractions.Atool consistingofPIMsandpotentialdrug–druginteractionswithin the same protocol provides more comprehensive quality assessment of drug-prescribing behavior to the elderly, which in turn may lead to better prescribing practices.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleEuropean journal of clinical pharmacology
Numberingvol. 68, no. 8, pp. 1123-38
p-ISSN0031-6970
e-ISSN1432-1041
DOIhttps://doi.org/10.1007/s00228-012-1238-1
URN:NBNurn:nbn:hr:239:699288
Publication2012
Document URLhttps://pubmed.ncbi.nlm.nih.gov/22362342/?from_term=Potentially+inappropriate+medications+in+the+elderly%3A+a+comprehensive+protocol.&from_pos=3
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2020-05-22 08:46:36