prikaz prve stranice dokumenta Assessment of Environmental and Hereditary Influence on Development of Pituitary Tumors Using Dermatoglyphic Traits and Their Potential as Screening Markers
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Scientific paper - Original scientific paper
Assessment of Environmental and Hereditary Influence on Development of Pituitary Tumors Using Dermatoglyphic Traits and Their Potential as Screening Markers
International Journal of Environmental Research and Public Health, 13 (2016), 3; 1-9. https://doi.org/10.3390/ijerph13030330
Gradišer, Marina; Matovinović Osvatić, Martina; Dilber, Dario; Bilić-Ćurćić, Ines

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Gradišer, M., Matovinović Osvatić, M., Dilber, D. & Bilić Ćurćić, I. (2016). Assessment of Environmental and Hereditary Influence on Development of Pituitary Tumors Using Dermatoglyphic Traits and Their Potential as Screening Markers. International Journal of Environmental Research and Public Health, 13. (3), 1-9. doi: 10.3390/ijerph13030330

Gradišer, Marina, et al. "Assessment of Environmental and Hereditary Influence on Development of Pituitary Tumors Using Dermatoglyphic Traits and Their Potential as Screening Markers." International Journal of Environmental Research and Public Health, vol. 13, no. 3, 2016, pp. 1-9. https://doi.org/10.3390/ijerph13030330

Gradišer, Marina, Martina Matovinović Osvatić, Dario Dilber and Ines Bilić Ćurćić. "Assessment of Environmental and Hereditary Influence on Development of Pituitary Tumors Using Dermatoglyphic Traits and Their Potential as Screening Markers." International Journal of Environmental Research and Public Health 13, no. 3 (2016): 1-9. https://doi.org/10.3390/ijerph13030330

Gradišer, M., et al. (2016) 'Assessment of Environmental and Hereditary Influence on Development of Pituitary Tumors Using Dermatoglyphic Traits and Their Potential as Screening Markers', International Journal of Environmental Research and Public Health, 13(3), pp. 1-9. doi: 10.3390/ijerph13030330

Gradišer M, Matovinović Osvatić M, Dilber D, Bilić Ćurćić I. Assessment of Environmental and Hereditary Influence on Development of Pituitary Tumors Using Dermatoglyphic Traits and Their Potential as Screening Markers. International Journal of Environmental Research and Public Health [Internet]. 2016 [cited 2024 December 10];13(3):1-9. doi: 10.3390/ijerph13030330

M. Gradišer, M. Matovinović Osvatić, D. Dilber and I. Bilić Ćurćić, "Assessment of Environmental and Hereditary Influence on Development of Pituitary Tumors Using Dermatoglyphic Traits and Their Potential as Screening Markers", International Journal of Environmental Research and Public Health, vol. 13, no. 3, pp. 1-9, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:888959. [Accessed: 10 December 2024]

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Metadata
Title (english)Assessment of Environmental and Hereditary Influence on Development of Pituitary Tumors Using Dermatoglyphic Traits and Their Potential as Screening Markers
AuthorMarina Gradišer
AuthorMartina Matovinović Osvatić
MBZ: 276326
AuthorDario Dilber
MBZ: 272063
AuthorInes Bilić-Ćurćić
MBZ: 268184
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Oncology
Abstract (english)
The aim of this study was to assess environmental and hereditary influence on development of pituitary tumors using dermatoglyphic traits. The study was performed on 126 patients of both genders with pituitary tumors (60 non-functional and 66 functional pituitary tumor patients) in comparison to the control group of 400 phenotypically healthy individuals. Statistical analysis of quantitative and qualitative traits of digito-palmar dermatoglyphics was performed, and hormonal status was determined according to the standard protocols. Although we did not find markers that could specifically distinguish functional from non-functional tumors, we have found markers predisposing to the development of tumors in general (a small number of ridges between triradius of both hands, a smaller number of ridges between the triradius of c–d rc R), those for endocrine dysfunction (increased number of arches and reduced number of whorls, difference of pattern distribution in the I3 and I4 interdigital space), and some that could potentially be attributed to patients suffering from pituitary tumors (small number of ridges for variables FRR 5, smaller number of ridges in the FRL 4 of both hands and difference of pattern distribution at thenar of I1 and I2 interdigital space). The usage of dermatoglyphic traits as markers of predisposition of pituitary tumor development could facilitate the earlier detection of patients in addition to standard methods, and possibly earlier treatment and higher survival rate. Finally, our results are consistent with the hypothesis about multifactorial nature of pituitary tumor etiology comprised of both gene instability and environmental factors.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleInternational Journal of Environmental Research and Public Health
Numberingvol. 13, no. 3, pp. 1-9
e-ISSN1660-4601
DOIhttps://doi.org/10.3390/ijerph13030330
URN:NBNurn:nbn:hr:239:888959
Publication2016
Document URLhttps://www.mdpi.com/1660-4601/13/3/330
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2019-10-29 07:46:11