prikaz prve stranice dokumenta More Hemodynamic Changes in Hypertensive Versus Non-hypertensive Patients Undergoing Breast Cancer Surgery in General Anesthesia - a Prospective Clinical Study
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Scientific paper - Original scientific paper
More Hemodynamic Changes in Hypertensive Versus Non-hypertensive Patients Undergoing Breast Cancer Surgery in General Anesthesia - a Prospective Clinical Study
Medicinski Glasnik, 6 (2009), 1; 97-103. urn:nbn:hr:239:005462
Kvolik, Slavica; Brozović, Gordana; Rakipović-Stojanović, Andreja; Drenjančević-Haršanji, Ivana; Kristek, Jozo; Šakić, Kata; Azenić-Venžera, Darija; Vidović, Dražen; Kovačić, Borna; Kristek, Gordana

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Kvolik, S., Brozović, G., Rakipović Stojanović, A., Drenjančević Haršanji, I., Kristek, J., Šakić, K. ... Kristek, G. (2009). More Hemodynamic Changes in Hypertensive Versus Non-hypertensive Patients Undergoing Breast Cancer Surgery in General Anesthesia - a Prospective Clinical Study. Medicinski Glasnik, 6. (1), 97-103. Retrieved from https://urn.nsk.hr/urn:nbn:hr:239:005462

Kvolik, Slavica, et al. "More Hemodynamic Changes in Hypertensive Versus Non-hypertensive Patients Undergoing Breast Cancer Surgery in General Anesthesia - a Prospective Clinical Study." Medicinski Glasnik, vol. 6, no. 1, 2009, pp. 97-103. https://urn.nsk.hr/urn:nbn:hr:239:005462

Kvolik, Slavica, Gordana Brozović, Andreja Rakipović Stojanović, Ivana Drenjančević Haršanji, Jozo Kristek, Kata Šakić, Darija Azenić Venžera, Dražen Vidović, Borna Kovačić and Gordana Kristek. "More Hemodynamic Changes in Hypertensive Versus Non-hypertensive Patients Undergoing Breast Cancer Surgery in General Anesthesia - a Prospective Clinical Study." Medicinski Glasnik 6, no. 1 (2009): 97-103. https://urn.nsk.hr/urn:nbn:hr:239:005462

Kvolik, S., et al. (2009) 'More Hemodynamic Changes in Hypertensive Versus Non-hypertensive Patients Undergoing Breast Cancer Surgery in General Anesthesia - a Prospective Clinical Study', Medicinski Glasnik, 6(1), pp. 97-103. Available at: https://urn.nsk.hr/urn:nbn:hr:239:005462 (Accessed 18 April 2024)

Kvolik S, Brozović G, Rakipović Stojanović A, Drenjančević Haršanji I, Kristek J, Šakić K, and sur.. More Hemodynamic Changes in Hypertensive Versus Non-hypertensive Patients Undergoing Breast Cancer Surgery in General Anesthesia - a Prospective Clinical Study. Medicinski Glasnik [Internet]. 2009 [cited 2024 April 18];6(1):97-103. Available at: https://urn.nsk.hr/urn:nbn:hr:239:005462

S. Kvolik, et al., "More Hemodynamic Changes in Hypertensive Versus Non-hypertensive Patients Undergoing Breast Cancer Surgery in General Anesthesia - a Prospective Clinical Study", Medicinski Glasnik, vol. 6, no. 1, pp. 97-103, 2009. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:005462. [Accessed: 18 April 2024]

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Metadata
Title (english)More Hemodynamic Changes in Hypertensive Versus Non-hypertensive Patients Undergoing Breast Cancer Surgery in General Anesthesia - a Prospective Clinical Study
AuthorSlavica Kvolik
MBZ: 259895
AuthorGordana Brozović
MBZ: 297164
AuthorAndreja Rakipović-Stojanović
MBZ: 344401
AuthorIvana Drenjančević-Haršanji
MBZ: 363764
AuthorJozo Kristek
MBZ: 224591
AuthorKata Šakić
MBZ: 168712
AuthorDarija Azenić-Venžera
AuthorDražen Vidović
MBZ: 332973
AuthorBorna Kovačić
MBZ: 342623
AuthorGordana Kristek
MBZ: 377931
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Anesthesiology and Reanimatology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Oncology
Abstract (english)
Aim Preoperative comorbidity may significantly influence the conduction of anesthesia and patients’ outcome. The aim of this study was to compare a number of anesthetic interventions and the use of non-anesthetic drugs in hypertensive and non-hypertensive patients during general anesthesia for moderately invasive surgery. Methods A total number of 88 elective hypertensive (n = 44) and non-hypertensive (n = 44) breast cancer patients were enrolled in the prospective study. Midazolam and infusion of normal saline were given before anesthesia. Etomidate, rocuronium, fentanyl, and sevoflurane up to the 1 MAC were used for the maintenance of anesthesia. Mean arterial pressure (MAP), pulse, core temperature and intraoperative use of all drugs were recorded. MAP was maintained by sevoflurane and infusion replacement. Urapidil and ethylephrine were given if MAP differed > or <30% of baseline, and atropine if heart rate <50 beats min-1. A statistical analysis was made using chi-square and Mann-Whitney tests. Results The highest MAP was 133±19.3 in hypertensive and 122±16.5 mmHg in the non-hypertensive patients (p<0.05). Hypertensive patients required more anesthetic balancing (42 vs. 23 interventions), more urapidil for intraoperative hypertension (13/44 vs. 2/44, p<0.05) and had more intraoperative hypotensive episodes (23 vs. 12; ns, p> 0.05). Intraoperative bradycardia (11/44 vs.7/44) and atropine applications (16 vs. 9, ns, p> 0.05) were similar in two groups. Conclusion Hypertensive patients required more anesthetic interventions and had higher consumption of vasoactive drugs during anesthesia for breast cancer surgery, suggesting their hemodynamic instability possibly related to the hypertension
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleMedicinski Glasnik
Numberingvol. 6, no. 1, pp. 97-103
p-ISSN1840-0132
e-ISSN1840-2445
URN:NBNurn:nbn:hr:239:005462
Publication2009
Document URLhttps://bib.irb.hr/datoteka/381796.Kvolik_more_haemodynamic_changes.pdf
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-ShareAlike 4.0 International (CC BY-SA 4.0) icon
Created on2020-02-05 08:40:45