prikaz prve stranice dokumenta Activity Cage as a Method to Analyze Functional Recovery After Sciatic Nerve Injury in Mice
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Scientific paper - Original scientific paper
Activity Cage as a Method to Analyze Functional Recovery After Sciatic Nerve Injury in Mice
Somatosensory and Motor Research, 24 (2007), 4; 213-219. https://doi.org/10.1080/08990220701745621
Pavić, Roman; Tvrdeić, Ante; Tot, Ozana Katarina; Heffer-Lauc, Marija

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Pavić, R., Tvrdeić, A., Tot, O. K. & Heffer Lauc, M. (2007). Activity Cage as a Method to Analyze Functional Recovery After Sciatic Nerve Injury in Mice. Somatosensory and Motor Research, 24. (4), 213-219. doi: 10.1080/08990220701745621

Pavić, Roman, et al. "Activity Cage as a Method to Analyze Functional Recovery After Sciatic Nerve Injury in Mice." Somatosensory and Motor Research, vol. 24, no. 4, 2007, pp. 213-219. https://doi.org/10.1080/08990220701745621

Pavić, Roman, Ante Tvrdeić, Ozana Katarina Tot and Marija Heffer Lauc. "Activity Cage as a Method to Analyze Functional Recovery After Sciatic Nerve Injury in Mice." Somatosensory and Motor Research 24, no. 4 (2007): 213-219. https://doi.org/10.1080/08990220701745621

Pavić, R., et al. (2007) 'Activity Cage as a Method to Analyze Functional Recovery After Sciatic Nerve Injury in Mice', Somatosensory and Motor Research, 24(4), pp. 213-219. doi: 10.1080/08990220701745621

Pavić R, Tvrdeić A, Tot OK, Heffer Lauc M. Activity Cage as a Method to Analyze Functional Recovery After Sciatic Nerve Injury in Mice. Somatosensory and Motor Research [Internet]. 2007 [cited 2024 December 10];24(4):213-219. doi: 10.1080/08990220701745621

R. Pavić, A. Tvrdeić, O. K. Tot and M. Heffer Lauc, "Activity Cage as a Method to Analyze Functional Recovery After Sciatic Nerve Injury in Mice", Somatosensory and Motor Research, vol. 24, no. 4, pp. 213-219, 2007. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:895832. [Accessed: 10 December 2024]

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Metadata
Title (english)Activity Cage as a Method to Analyze Functional Recovery After Sciatic Nerve Injury in Mice
AuthorRoman Pavić
MBZ: 285214
AuthorAnte Tvrdeić
MBZ: 157335
AuthorOzana Katarina Tot
MBZ: 344381
AuthorMarija Heffer-Lauc
MBZ: 178985
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Medical Microbiology
Abstract (english)
The aim of this paper is to show the activity cage as a viable method for tracking functional nerve recovery. The activity cage measures spontaneous coordinate activity, meaning movement in either the horizontal or vertical plane, of experimental animals within a specified amount of time. This uses a minimum of researcher time conducting functional testing to determine functional recovery of the nerve. Using microsurgical forceps, a crush injury was inflicted unilaterally, on the left side, upon the 4-month-old C3H mice creating a very high degree of pressure for 6 s upon the exposed sciatic nerve. The locomotion function of the mice was evaluated using the activity cage preoperatively, 1, 7, 14, 21, and 28 days after the surgical procedure. We found that using the activity cage functional recovery occurred by 14 days after nerve crush injury. It was also shown that, coinciding with functional recovery, immunohistochemistry changes for GD1a and nNOS appeared at the level of L4, where the sciatic nerve joins the spinal column. GD1a and nNOS have both been linked to regenerative processes in mammalian nervous systems
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleSomatosensory and Motor Research
Numberingvol. 24, no. 4, pp. 213-219
p-ISSN0899-0220
e-ISSN1369-1651
DOIhttps://doi.org/10.1080/08990220701745621
URN:NBNurn:nbn:hr:239:895832
Publication2007
Document URLhttps://www.tandfonline.com/doi/full/10.1080/08990220701745621
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-03-27 10:18:34