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Scientific paper - Original scientific paper
Clinical Characteristics of Patients with Spondyloarthritides and HLA-B27 Positive Antigen
Collegium antropologicum, 35 (2011), 2; 397-402. urn:nbn:hr:239:529237
Glasnović, Marija; Bošnjak, Ivica; Šram, Miroslav; Vranješ, Željko; Včev, Aleksandar; Dobrošević, Blaženka; Sinčić Petričević, Jasminka; Horvatić, Elizabeta; Orkić, Želimir; Tadžić, Refmir; Soldo, Anamarija; Šišljagić, Dina; Dinjar, Kristijan

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Glasnović, M., Bošnjak, I., Šram, M., Vranješ, Ž., Včev, A., Dobrošević, B. ... Dinjar, K. (2011). Clinical Characteristics of Patients with Spondyloarthritides and HLA-B27 Positive Antigen. Collegium antropologicum, 35. (2), 397-402. Retrieved from https://urn.nsk.hr/urn:nbn:hr:239:529237

Glasnović, Marija, et al. "Clinical Characteristics of Patients with Spondyloarthritides and HLA-B27 Positive Antigen." Collegium antropologicum, vol. 35, no. 2, 2011, pp. 397-402. https://urn.nsk.hr/urn:nbn:hr:239:529237

Glasnović, Marija, Ivica Bošnjak, Miroslav Šram, Željko Vranješ, Aleksandar Včev, Blaženka Dobrošević, Jasminka Sinčić Petričević, et al. "Clinical Characteristics of Patients with Spondyloarthritides and HLA-B27 Positive Antigen." Collegium antropologicum 35, no. 2 (2011): 397-402. https://urn.nsk.hr/urn:nbn:hr:239:529237

Glasnović, M., et al. (2011) 'Clinical Characteristics of Patients with Spondyloarthritides and HLA-B27 Positive Antigen', Collegium antropologicum, 35(2), pp. 397-402. Available at: https://urn.nsk.hr/urn:nbn:hr:239:529237 (Accessed 17 November 2024)

Glasnović M, Bošnjak I, Šram M, Vranješ Ž, Včev A, Dobrošević B, and sur.. Clinical Characteristics of Patients with Spondyloarthritides and HLA-B27 Positive Antigen. Collegium antropologicum [Internet]. 2011 [cited 2024 November 17];35(2):397-402. Available at: https://urn.nsk.hr/urn:nbn:hr:239:529237

M. Glasnović, et al., "Clinical Characteristics of Patients with Spondyloarthritides and HLA-B27 Positive Antigen", Collegium antropologicum, vol. 35, no. 2, pp. 397-402, 2011. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:529237. [Accessed: 17 November 2024]

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Metadata
Title (english)Clinical Characteristics of Patients with Spondyloarthritides and HLA-B27 Positive Antigen
Title (croatian)Klinička obilježja pacijenata sa spondiloartritisima i hla-b27 pozitivnim antigenom
AuthorMarija Glasnović
MBZ: 254820
AuthorIvica Bošnjak
AuthorMiroslav Šram
MBZ: 364605
AuthorŽeljko Vranješ
MBZ: 201762
AuthorAleksandar Včev
MBZ: 141721
AuthorBlaženka Dobrošević
AuthorJasminka Sinčić Petričević
AuthorElizabeta Horvatić
MBZ: 334863
AuthorŽelimir Orkić
MBZ: 357670
AuthorRefmir Tadžić
MBZ: 350034
AuthorAnamarija Soldo
AuthorDina Šišljagić
AuthorKristijan Dinjar
MBZ: 297280
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Otorhinolaryngology
Abstract (english)
The aim of this study was to present our experiences in diagnosing spondyloarthritides (SpA), and to list the most common clinical features of HLA-B 27 positive patients.The study included 65 HLA-B 27 positive patients with confirmed diagnosis of ankylosing spondylitis(AS) and psoriatic arthritis (PsA) who were analyzed between 2009 and 2010 in Clinic of Internal Medicine in Osijek. The diagnosis of seronegative spondyloarthritides was based on the ASAS (Assessment in AS Working Group) classification criteria for axial and then supplemented with ASAS criteria for peripheral SpA and was confirmed by radiological techniques. For diagnosing the ankylosing spondylitis (AS), there have been applied the modified New York criteria. Radiological criteria for definite sacroiliitis according to the modified New York criteria is bilateral sacroiliitis, grade 2–4 (2) or unilateral sacroiliitis, grade 3–4. For diagnosing the psoriatic arthritis (PsA), there were used CASPAR diagnostic criteria. Other features of SpA are defined within the existing classification criteria. HLA-B27 antigen was determined by direct immune-fluorescence technique using flow cytometer. The average age of patients was 50.34 years, of whom 27 female (41.53%), 38 male (58.46%). Duration of illness was 15.79 years on average.With 75.38% of patients, there had been determined the diagnosis of AS; 24.62% of patients had the diagnosis of PsA. The most common clinical characteristics that patients had were: inflammatory back pain (pain Inflammation along the lumbosacral spine), peripheral arthritis, intermittent pain in the gluteus, sacroiliitis, enthesitis, uveitis, dactilitis.
Abstract (croatian)
Cilj ovog rada bio je prikazati naša iskustva u dijagnostici spondiloartritisa (SpA) te navesti najtipičnija klinička obilježja HLA-B27 pozitivnih bolesnika. U istraživanju je uključeno 65 HLA-B 27 pozitivnih bolesnika s potvr|enom dijagnozom ankilozantnog spondilitisa (AS) i psorijatičnog artritisa (PsA) koji su tijekom 2009 i 2010 godine liječeni na Internoj klinici u Osijeku. Dijagnoza seronegativnih spondiloartritisa temeljila se na ASAS (Assessment in AS working group) klasifikacijskim kriterijima za aksijalni i periferni SpA i bila potvr|ena radiološkim metodama. Za dijagnosticiranje ankilozantnog spondilitisa (AS) primijenili su se modificirani New york kriteriji. Radiološki kriterij za definitivni sakroileitis prema modificiranim New York kriterijima je bilateralni sakroiliitis stupnja 2–4 (2) ili unilateralni sakroiliitis stupnja 3–4. Za dijagnozu psorijatičnog artritisa (PsA) korišteni su CASPAR dijagnostički kriteriji. Ostale značajke SpA definirane su u sklopu postojećih klasifikacijskih kriterija. HLA-B27 antigen je određivan je direktnom imunofluorescentnom metodom na protočnom citometru. Prosječna starost pacijenata bila je 50,34 godina, od kojih je 27 žena (41,53%), 38 muških (58,46%). Trajanje bolesti bilo je u prosjeku 15,79 godina. U 75,38 % bolesnika postavljena je dijagnoza AS; 24.62% bolesnika imalo je dijagnozu PSA. Najčešće kliničke karakteristike koje su pacijenti imali bili su: upalna križobolja (inflamatorna bol duž lumbosakralnog dijala kralježnice), periferni artritis, naizmjenična bol u gluteusima, sakroiliitis, entezitis, uveitis, daktilitis. Ovo naše istraživanje je pokazalo da se kliničke značajke HLA B 27 pozitivnih pacijenata sa SpA u Istočnoj Slavoniji ne razlikuju od kliničkih manifestacija pacijenata sa SpA u drugim dijelovima Europe koje su iznesene u različitim studijama.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCollegium antropologicum
Numberingvol. 35, no. 2, pp. 397-402
p-ISSN0350-6134
URN:NBNurn:nbn:hr:239:529237
Publication2011
Document URLhttps://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=102894
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-04-02 07:55:27