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Scientific paper - Case study
Falsely Elevated Serum Oestradiol due to Exemestane Therapy
Annals of Clinical Biochemistry, 54 (2017), 3; 402-405. https://doi.org/10.1177/0004563216674031
Mandić, Sanja; Kratzsch, Jurgen; Mandić, Dario; Debeljak, Željko; Lukić, Iva; Horvat, Vesna; Gaudl, Alexander; Šerić, Vatroslav

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Mandić, S., Kratzsch, J., Mandić, D., Debeljak, Ž., Lukić, I., Horvat, V. ... Šerić, V. (2017). Falsely Elevated Serum Oestradiol due to Exemestane Therapy. Annals of Clinical Biochemistry, 54. (3), 402-405. doi: 10.1177/0004563216674031

Mandić, Sanja, et al. "Falsely Elevated Serum Oestradiol due to Exemestane Therapy." Annals of Clinical Biochemistry, vol. 54, no. 3, 2017, pp. 402-405. https://doi.org/10.1177/0004563216674031

Mandić, Sanja, Jurgen Kratzsch, Dario Mandić, Željko Debeljak, Iva Lukić, Vesna Horvat, Alexander Gaudl and Vatroslav Šerić. "Falsely Elevated Serum Oestradiol due to Exemestane Therapy." Annals of Clinical Biochemistry 54, no. 3 (2017): 402-405. https://doi.org/10.1177/0004563216674031

Mandić, S., et al. (2017) 'Falsely Elevated Serum Oestradiol due to Exemestane Therapy', Annals of Clinical Biochemistry, 54(3), pp. 402-405. doi: 10.1177/0004563216674031

Mandić S, Kratzsch J, Mandić D, Debeljak Ž, Lukić I, Horvat V, and sur.. Falsely Elevated Serum Oestradiol due to Exemestane Therapy. Annals of Clinical Biochemistry [Internet]. 2017 [cited 2025 January 22];54(3):402-405. doi: 10.1177/0004563216674031

S. Mandić, et al., "Falsely Elevated Serum Oestradiol due to Exemestane Therapy", Annals of Clinical Biochemistry, vol. 54, no. 3, pp. 402-405, 2017. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:115455. [Accessed: 22 January 2025]

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Metadata
Title (english)Falsely Elevated Serum Oestradiol due to Exemestane Therapy
AuthorSanja Mandić
MBZ: 349013
AuthorJurgen Kratzsch
AuthorDario Mandić
MBZ: 367140
AuthorŽeljko Debeljak
MBZ: 296571
AuthorIva Lukić
AuthorVesna Horvat
MBZ: 349024
AuthorAlexander Gaudl
AuthorVatroslav Šerić
MBZ: 193563
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Oncology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Clinical Immunology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Abstract (english)
In this study, we present a case of falsely elevated oestradiol (E2) concentration, determined by two immunoassays, in a breast cancer patient receiving exemestane therapy. The positive bias of immunochemical measurements was revealed using liquid chromatography tandem mass spectrometry which showed undetectable E2 concentration. The discrepancy is expected to be a consequence of the structural resemblance of E2 and exemestane sharing the same steroidal backbone. Inaccurate laboratory findings in therapy monitoring, as in this case, may lead to unnecessary changes of therapy.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleAnnals of Clinical Biochemistry
Numberingvol. 54, no. 3, pp. 402-405
p-ISSN0004-5632
e-ISSN1758-1001
DOIhttps://doi.org/10.1177/0004563216674031
URN:NBNurn:nbn:hr:239:115455
Publication2017
Document URLhttps://journals.sagepub.com/doi/full/10.1177/0004563216674031?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-05-04 10:06:26