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Scientific paper - Review paper
Pathologic Patterns of Interleukin 10 Expression – A Review
Biochemia Medica, 25 (2015), 1; 36-48. https://doi.org/10.11613/BM.2015.004
Trifunović, Jasenka; Miller, Larisa; Debeljeak, Željko; Horvat, Vesna

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Trifunović, J., Miller, L., Debeljeak, Ž. & Horvat, V. (2015). Pathologic Patterns of Interleukin 10 Expression – A Review. Biochemia Medica, 25. (1), 36-48. doi: 10.11613/BM.2015.004

Trifunović, Jasenka, et al. "Pathologic Patterns of Interleukin 10 Expression – A Review." Biochemia Medica, vol. 25, no. 1, 2015, pp. 36-48. https://doi.org/10.11613/BM.2015.004

Trifunović, Jasenka, Larisa Miller, Željko Debeljeak and Vesna Horvat. "Pathologic Patterns of Interleukin 10 Expression – A Review." Biochemia Medica 25, no. 1 (2015): 36-48. https://doi.org/10.11613/BM.2015.004

Trifunović, J., et al. (2015) 'Pathologic Patterns of Interleukin 10 Expression – A Review', Biochemia Medica, 25(1), pp. 36-48. doi: 10.11613/BM.2015.004

Trifunović J, Miller L, Debeljeak Ž, Horvat V. Pathologic Patterns of Interleukin 10 Expression – A Review. Biochemia Medica [Internet]. 2015 [cited 2024 November 16];25(1):36-48. doi: 10.11613/BM.2015.004

J. Trifunović, L. Miller, Ž. Debeljeak and V. Horvat, "Pathologic Patterns of Interleukin 10 Expression – A Review", Biochemia Medica, vol. 25, no. 1, pp. 36-48, 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:298868. [Accessed: 16 November 2024]

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Metadata
Title (english)Pathologic Patterns of Interleukin 10 Expression – A Review
AuthorJasenka Trifunović
AuthorLarisa Miller
AuthorŽeljko Debeljeak
AuthorVesna Horvat
MBZ: 349024
Author's institution(Clinical hospital center Osijek)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pathophysiology
Abstract (english)
Interleukin 10 (IL-10) is important pleiotropic immunoregulatory cytokine which gene is located on chromosome 1 at 1q31-32. There are many genetic variants of IL-10 gene. However, the most studied are two dinucleotide repeats (microsatellites), IL10.G and IL10.R, located 1.2 kb and 4 kb upstream of the transcription start site and three single nucleotide polymorphisms (SNPs) -1082(G/A), -819(C/T) and -592(C/A). A large number of studies have shown that IL-10 gene polymorphisms are associated with different diseases and play an important role in pathophysiology and clinical course of these diseases. This review summarizes published literature knowledge about the association of IL-10 polymorphisms and expression patterns with asthma, systemic lupus erythematosus, psoriasis, inflammatory bowel disease, rheumatoid arthritis, tuberculosis and some neoplasms.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleBiochemia Medica
Numberingvol. 25, no. 1, pp. 36-48
p-ISSN1330-0962
e-ISSN1846-7482
DOIhttps://doi.org/10.11613/BM.2015.004
URN:NBNurn:nbn:hr:239:298868
Publication2015
Document URLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401305/
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2020-05-05 10:26:34