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Scientific paper - Original scientific paper
Prevalence and Significance of Vaginal Group B Streptococcus olonization in Pregnant Women from Osijek, Croatia
Collegium antropologicum, 35 (2011), 1; 21-26. urn:nbn:hr:239:896272
Muller-Vranješ, Andrijana; Puntarić, Dinko; Čuržik, Darko; Šijanović, Siniša; Topolovec, Zlatko; Kasač, Zoran; Miškulin, Maja

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Muller Vranješ, A., Puntarić, D., Čuržik, D., Šijanović, S., Topolovec, Z., Kasač, Z. & Miškulin, M. (2011). Prevalence and Significance of Vaginal Group B Streptococcus olonization in Pregnant Women from Osijek, Croatia. Collegium antropologicum, 35. (1), 21-26. Retrieved from https://urn.nsk.hr/urn:nbn:hr:239:896272

Muller Vranješ, Andrijana, et al. "Prevalence and Significance of Vaginal Group B Streptococcus olonization in Pregnant Women from Osijek, Croatia." Collegium antropologicum, vol. 35, no. 1, 2011, pp. 21-26. https://urn.nsk.hr/urn:nbn:hr:239:896272

Muller Vranješ, Andrijana, Dinko Puntarić, Darko Čuržik, Siniša Šijanović, Zlatko Topolovec, Zoran Kasač and Maja Miškulin. "Prevalence and Significance of Vaginal Group B Streptococcus olonization in Pregnant Women from Osijek, Croatia." Collegium antropologicum 35, no. 1 (2011): 21-26. https://urn.nsk.hr/urn:nbn:hr:239:896272

Muller Vranješ, A., et al. (2011) 'Prevalence and Significance of Vaginal Group B Streptococcus olonization in Pregnant Women from Osijek, Croatia', Collegium antropologicum, 35(1), pp. 21-26. Available at: https://urn.nsk.hr/urn:nbn:hr:239:896272 (Accessed 07 December 2024)

Muller Vranješ A, Puntarić D, Čuržik D, Šijanović S, Topolovec Z, Kasač Z, and sur.. Prevalence and Significance of Vaginal Group B Streptococcus olonization in Pregnant Women from Osijek, Croatia. Collegium antropologicum [Internet]. 2011 [cited 2024 December 07];35(1):21-26. Available at: https://urn.nsk.hr/urn:nbn:hr:239:896272

A. Muller Vranješ, et al., "Prevalence and Significance of Vaginal Group B Streptococcus olonization in Pregnant Women from Osijek, Croatia", Collegium antropologicum, vol. 35, no. 1, pp. 21-26, 2011. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:896272. [Accessed: 07 December 2024]

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Metadata
Title (english)Prevalence and Significance of Vaginal Group B Streptococcus olonization in Pregnant Women from Osijek, Croatia
Title (croatian)Učestalost i značaj kolonizacije rodnice streptokokom grupe B trudnica s područja grada Osijeka, Hrvatska
AuthorAndrijana Muller-Vranješ
MBZ: 294701
AuthorDinko Puntarić
MBZ: 202820
AuthorDarko Čuržik
MBZ: 193866
AuthorSiniša Šijanović
MBZ: 221514
AuthorZlatko Topolovec
MBZ: 300264
AuthorZoran Kasač
AuthorMaja Miškulin
MBZ: 290921
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract (english)
The aim of the study was to determine the prevalence of vaginal group B streptococcus (GBS) colonization in pregnant women from Osijek area, the possible effect of GBS colonization on pregnancy outcome and neonatal complications and the role of intrapartum prophylaxis in this context. This retrospective case-control study took place at the Department of Gynecology and Obstetrics, Osijek University Hospital Center from December 2003 to June 2006. A total of 118 pregnant women was enrolled in study and divided into two groups: 59 women in 35th–37th week of gestation, free from risk factors for infection (control group); and 59 women in 25th–41st week of gestation with risk factors for infection. Low vaginal swab for GBS isolation and identification on selective and enriched medium was obtained from each woman. GBS colonization was recorded in 29 (24.6%) women: 12 (20.3%) control and 17 (28.8%) women at risk of infection, yielding a statistically non-significant difference (c 2=1.480489; p<0.48). Early neonatal infection was observed in six (20.7%) neonates born to 29 mothers with GBS colonization, pointing to a correlation between vaginal GBS colonization and early neonatal infection (rs=0.99). Early perinatal infection was found in 22 (18.6%) neonates, including 17 (28.8%) pregnancies with risk factors, pointing to a significant correlation between vaginal GBS colonization, risk factors and early perinatal infection (c 2=88.68; p<0.001); however, gestational age and pregnancy outcome were not influenced by GBS colonization. In eight (36.4%) newborns, early neonatal infection developed in spite of intrapartum administration of antibiotics; three of these children were born to GBS positive mothers, and perinatal GBS infection was demonstrated in one (0.84%) child. Study results revealed a relatively high rate of GBS colonization in the population of pregnant women in Croatia, occasionally leading to early neonatal infection. Large studies are needed to develop national strategy for the prevention of GBS infection in Croatia.
Abstract (croatian)
Cilj istraživanja bio je utvrditi učestalost kolonizacije rodnice streptokokom grupe B (GBS) trudnica grada Osijeka. Istražiti ima li utvrđena kolonizacija i kakav utjecaj na ishod trudnoće te na nastanak komplikacija kod rođene djece, te kakva je kod toga uloga i značaj intrapartalne profilakse. Među trudnicama s područja grada Osijeka praćenim na Odjelu za ginekologiju i opstetriciju Kliničkog bolničkog centra Osijek, u razdoblju od prosinca 2003. godine do lipnja 2006. godine, provedeno je poprečno-presječno istraživanje. Obrađeno je 118 trudnica podijeljenih u dvije skupine. U probirnoj (kontrolnoj) skupini bilo je 59 trudnica u dobi od 35 do 37 tjedana trudnoće, bez rizičnih čimbenika za infekciju, a u drugoj 59 trudnica s rizičnim čimbenicima za infekciju, trajanja trudnoće od 25 do 41 tjedna. Svakoj trudnici uzet je donji vaginalni obrisak radi izolacije i identifikacije GBS na selektivnoj i obogaćenoj podlozi. Kolonizacija GBS-om utvrđena je kod 29 (24.6%) žena. U probirnoj skupini kod 12 (20.3%), a u rizičnoj skupini 17 (28.8%), bez statistički uočene razlike (c2=1.480489, p<0.48). Kod 6 (20.7%) novorođenčadi od 29 koloniziranih žena GBS-om utvrđena je rana neonatalna infekcija, što govori o korelaciji kolonizacije rodnice GBS-om i rane neonatalne infekcije (rs=0.99). Rana perinatalna infekcija javila se je kod 22 (18.6%) novorođenčadi, pri čemu 17 (28.8%) iz trudnoća žena s rizičnim faktorima, što ukazuje da postoji značajna povezanost kolonizacije rodnice GBS-om, rizičnih faktora i rane infekcije djeteta (c2=88.68, p<0.001), no kolonizacija ne utječe na trajanje i ishod trudnoće. Kod 8 (36.4%) djece se je rana neonatalna infekcija javila usprkos intrapartalnoj primjeni antibiotika, 3 od njih bila su djeca GBS pozitivnih majki, a kod jednog (0.84%) od njih dokazana je perinatalna infekcija GBS-om. Istraživanje je pokazalo kako je i u Hrvatskoj kolonizacija GBS-om značajna pojava u populaciji trudnica, koja u određenog broja trudnica može rezultirati razvojem rane neonatalne infekcije u njihove novorođenčadi. Nužno je provesti šira i sveobuhvatnija istraživanja temeljem kojih će se donijeti nacionalna strategija za prevenciju neonatalnih GBS infekcija u Hrvatskoj.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCollegium antropologicum
Numberingvol. 35, no. 1, pp. 21-26
p-ISSN0350-6134
URN:NBNurn:nbn:hr:239:896272
Publication2011
Document URLhttps://hrcak.srce.hr/64724
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-05-18 10:25:38