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Scientific paper - Original scientific paper
Breast Cancer in Young Women: Pathologic and Immunohistochemical Features
Acta clinica Croatica, 57 (2018), 3; 497-502. https://doi.org/10.20471/acc.2018.57.03.13
Erić, Ivan; Erić Petek, Anamarija; Kristek, Jozo; Koprivčić, Ivan; Babić, Marko

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Erić, I., Erić Petek, A., Kristek, J., Koprivčić, I. & Babić, M. (2018). Breast Cancer in Young Women: Pathologic and Immunohistochemical Features. Acta clinica Croatica, 57. (3), 497-502. doi: 10.20471/acc.2018.57.03.13

Erić, Ivan, et al. "Breast Cancer in Young Women: Pathologic and Immunohistochemical Features." Acta clinica Croatica, vol. 57, no. 3, 2018, pp. 497-502. https://doi.org/10.20471/acc.2018.57.03.13

Erić, Ivan, Anamarija Erić Petek, Jozo Kristek, Ivan Koprivčić and Marko Babić. "Breast Cancer in Young Women: Pathologic and Immunohistochemical Features." Acta clinica Croatica 57, no. 3 (2018): 497-502. https://doi.org/10.20471/acc.2018.57.03.13

Erić, I., et al. (2018) 'Breast Cancer in Young Women: Pathologic and Immunohistochemical Features', Acta clinica Croatica, 57(3), pp. 497-502. doi: 10.20471/acc.2018.57.03.13

Erić I, Erić Petek A, Kristek J, Koprivčić I, Babić M. Breast Cancer in Young Women: Pathologic and Immunohistochemical Features. Acta clinica Croatica [Internet]. 2018 [cited 2024 October 28];57(3):497-502. doi: 10.20471/acc.2018.57.03.13

I. Erić, A. Erić Petek, J. Kristek, I. Koprivčić and M. Babić, "Breast Cancer in Young Women: Pathologic and Immunohistochemical Features", Acta clinica Croatica, vol. 57, no. 3, pp. 497-502, 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:504228. [Accessed: 28 October 2024]

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Metadata
Title (english)Breast Cancer in Young Women: Pathologic and Immunohistochemical Features
Title (croatian)Rak dojke u mladih žena: patološka i imunohistokemijska obilježja
AuthorIvan Erić
AuthorAnamarija Erić Petek
MBZ: 287863
AuthorJozo Kristek
MBZ: 224591
AuthorIvan Koprivčić
MBZ: 311933
AuthorMarko Babić
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Surgery
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Oncology
Abstract (english)
A young woman with breast cancer is considered to be a woman younger than 40. According to the literature, breast cancer in the population of young women usually is of a higher histologic grade, unfavorable hormonal status, and overall higher mortality rate when compared with breast cancer occurring in older population. We compared pathologic and immunohistochemical features of breast carcinoma in women under 40 years of age with the respective features in women over 60 years of age. The following parameters were observed in these two groups: tumor size, lymph node status, histologic grade, hormonal receptor status, Ki-67 prognostic index, Her2/neu status, and histologic type of the tumor. Early onset breast carcinoma was found to have a higher frequency of tumor grade 3 (29% vs. 17%) and estrogen receptor negativity (45% vs. 23%). In the group of young women, breast carcinoma was mostly multicentric (23% vs. 5%), triple-negative (32% vs. 10%), and was found to have higher proliferation index Ki-67 (25% vs. 10%). Our results confirmed differences between the young and older groups of patients. In the group of young women, we found predominantly unfavorable prognostic parameters of the disease.
Abstract (croatian)
Mladom ženom s rakom dojke smatra se žena mlađa od 40 godina. Prema literaturi rak dojke u populaciji mladih žena ima obično viši histološki stupanj i nepovoljan hormonski status. Puno je veći postotak smrtnosti u mladoj populaciji nego kada se karcinom javlja u starijoj životnoj dobi. Usporedili smo patološka i imunohistokemijska obilježja karcinoma dojke kod žena ispod 40 godina s odgovarajućim obilježjima među ženama iznad 60 godina. Sljedeći parametri su promatrani kod ove dvije skupine: veličina tumora, stanje limfnih čvorova, histološki gradus, status hormonskih receptora, prognostički indeks Ki-67, status Her2/neu i histološki tip tumora. Za karcinom dojke kod mladih žena utvrđeno je da ima veću učestalost tumora histološkog gradusa 3 (29% prema 17%) i negativnog statusa estrogenskih receptora (45% prema 23%). U skupini mladih žena rak dojke je uglavnom multicentričan (23% prema 5%), trostruko negativan (32% prema 10%) i ustanovljeno je da ima veći proliferacijski indeks Ki-67 (25% prema 10%). Naši rezultati potvrđuju razlike između mlade i starije skupine bolesnica. U skupini mladih žena utvrđeni su pretežito nepovoljni prognostički parametri bolesti.
Keywords (english)
Keywords (croatian)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleActa clinica Croatica
Numberingvol. 57, no. 3, pp. 497-502
p-ISSN0353-9466
e-ISSN1333-9451
DOIhttps://doi.org/10.20471/acc.2018.57.03.13
URN:NBNurn:nbn:hr:239:504228
Publication2018
Document URLhttps://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=315417
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2019-09-26 11:30:02