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In Vitro Effect of Subminimal Inhibitory Concentrations of Antibiotics on the Biofilm Formation Ability of Acinetobacter Baumannii Clinical Isolates
Journal of Chemotherapy, 30 (2018), 1; 16-24. https://doi.org/10.1080/1120009X.2017.1378835
Bogdan, Maja; Drenjančević, Domagoj; Haršanji Drenjančević, Ivana; Bedenić, Branka; Zujić Atalić, Vlasta; Talapko, Jasminka; Vuković, Dubravka

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Bogdan, M., Drenjančević, D., Haršanji Drenjančević, I., Bedenić, B., Zujić Atalić, V., Talapko, J. i Vuković, D. (2018). In Vitro Effect of Subminimal Inhibitory Concentrations of Antibiotics on the Biofilm Formation Ability of Acinetobacter Baumannii Clinical Isolates. Journal of Chemotherapy, 30. (1), 16-24. doi: 10.1080/1120009X.2017.1378835

Bogdan, Maja, et al. "In Vitro Effect of Subminimal Inhibitory Concentrations of Antibiotics on the Biofilm Formation Ability of Acinetobacter Baumannii Clinical Isolates." Journal of Chemotherapy, vol. 30, br. 1, 2018, str. 16-24. https://doi.org/10.1080/1120009X.2017.1378835

Bogdan, Maja, Domagoj Drenjančević, Ivana Haršanji Drenjančević, Branka Bedenić, Vlasta Zujić Atalić, Jasminka Talapko i Dubravka Vuković. "In Vitro Effect of Subminimal Inhibitory Concentrations of Antibiotics on the Biofilm Formation Ability of Acinetobacter Baumannii Clinical Isolates." Journal of Chemotherapy 30, br. 1 (2018): 16-24. https://doi.org/10.1080/1120009X.2017.1378835

Bogdan, M., et al. (2018) 'In Vitro Effect of Subminimal Inhibitory Concentrations of Antibiotics on the Biofilm Formation Ability of Acinetobacter Baumannii Clinical Isolates', Journal of Chemotherapy, 30(1), str. 16-24. doi: 10.1080/1120009X.2017.1378835

Bogdan M, Drenjančević D, Haršanji Drenjančević I, Bedenić B, Zujić Atalić V, Talapko J, i sur.. In Vitro Effect of Subminimal Inhibitory Concentrations of Antibiotics on the Biofilm Formation Ability of Acinetobacter Baumannii Clinical Isolates. Journal of Chemotherapy [Internet]. 2018. [pristupljeno 22.11.2024.];30(1):16-24. doi: 10.1080/1120009X.2017.1378835

M. Bogdan, et al., "In Vitro Effect of Subminimal Inhibitory Concentrations of Antibiotics on the Biofilm Formation Ability of Acinetobacter Baumannii Clinical Isolates", Journal of Chemotherapy, vol. 30, br. 1, str. 16-24, 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:239:928136. [Citirano: 22.11.2024.]

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Podaci o radu
Naslov (engleski)In Vitro Effect of Subminimal Inhibitory Concentrations of Antibiotics on the Biofilm Formation Ability of Acinetobacter Baumannii Clinical Isolates
AutorMaja Bogdan
MBZ: 364346
AutorDomagoj Drenjančević
MBZ: 297300
AutorIvana Haršanji Drenjančević
MBZ: 363764
AutorBranka Bedenić
MBZ: 178926
AutorVlasta Zujić Atalić
MBZ: 375251
AutorJasminka Talapko
MBZ: 377874
AutorDubravka Vuković
Autorova ustanova(Klinički bolnički centar Osijek)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Autorova ustanovaSveučilište Josipa Jurja Strossmayera u Osijeku
Medicinski fakultet Osijek
(Katedra za mikrobiologiju, parazitologiju i kliničko-laboratorijsku dijagnostiku)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Infektologija
Sažetak (engleski)
The ability of A cinetobacter baumannii strains to form biofilm is one of the most important virulence factor which enables bacterial survival in a harsh environment and decreases antibiotic concentration as well. Subminimal inhibitory concentrations (subMICs) of antibiotics may change bacterial ultrastructure or have an influence on some different molecular mechanisms resulting in morphological or physiological changes in bacteria itself. The aim of this study was to determine effects of 1/2, 1/4, 1/8 and 1/16 minimal inhibitory concentrationsof imipenem, ampicillin-sulbactam, azithromycin, rifampicin and colistin on biofilm formation ability of 22 biofilm non-producing and 46 biofilm producing A. baumannii strains (30 weak producing strains and 16 moderate producing strains). Results of this study indicate that 1/2-1/16 MICs of imipenem, azithromycin, and rifampicin can reduce bacterial biofilm formation ability in moderate producing strains (p < 0.05), whereas 1/16 MIC of imipenem and 1/4-1/8 MICs of rifampicin reduce the biofilm formation in weak producing strains (p < 0.05). Statisticaly significant effect was detected among biofilm non-producing strains after their exposure to 1/16 MIC of azithromycin (p = 0.039). SubMICs of ampicillin-sulbactam and colistin did not have any significant effect on biofilm formation among tested A. baumannii strains.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Chemotherapy
Brojčani podacivol. 30, br. 1, str. 16-24
p-ISSN1120-009X
e-ISSN1973-9478
DOIhttps://doi.org/10.1080/1120009X.2017.1378835
URN:NBNurn:nbn:hr:239:928136
Datum objave publikacije2018
URL dokumentahttps://www.tandfonline.com/doi/full/10.1080/1120009X.2017.1378835?scroll=top&needAccess=true
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 3.0 (CC BY 3.0)
Datum i vrijeme pohrane2020-01-31 08:10:56