prikaz prve stranice dokumenta Potentially Inappropriate Prescribing to the Elderly: Comparison of new Protocol to Beers Criteria With Relation to Hospitalizations for ADRs
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Potentially Inappropriate Prescribing to the Elderly: Comparison of new Protocol to Beers Criteria With Relation to Hospitalizations for ADRs
European Journal of Clinical Pharmacology, 70 (2014), 4; 483-490. https://doi.org/10.1007/s00228-014-1648-3
Mimica Matanović, Suzana; Vlahović-Palčevski, Vera

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Mimica Matanović, S. i Vlahović Palčevski, V. (2014). Potentially Inappropriate Prescribing to the Elderly: Comparison of new Protocol to Beers Criteria With Relation to Hospitalizations for ADRs. European Journal of Clinical Pharmacology, 70. (4), 483-490. doi: 10.1007/s00228-014-1648-3

Mimica Matanović, Suzana i Vera Vlahović Palčevski. "Potentially Inappropriate Prescribing to the Elderly: Comparison of new Protocol to Beers Criteria With Relation to Hospitalizations for ADRs." European Journal of Clinical Pharmacology, vol. 70, br. 4, 2014, str. 483-490. https://doi.org/10.1007/s00228-014-1648-3

Mimica Matanović, Suzana i Vera Vlahović Palčevski. "Potentially Inappropriate Prescribing to the Elderly: Comparison of new Protocol to Beers Criteria With Relation to Hospitalizations for ADRs." European Journal of Clinical Pharmacology 70, br. 4 (2014): 483-490. https://doi.org/10.1007/s00228-014-1648-3

Mimica Matanović, S. i Vlahović Palčevski, V. (2014) 'Potentially Inappropriate Prescribing to the Elderly: Comparison of new Protocol to Beers Criteria With Relation to Hospitalizations for ADRs', European Journal of Clinical Pharmacology, 70(4), str. 483-490. doi: 10.1007/s00228-014-1648-3

Mimica Matanović S, Vlahović Palčevski V. Potentially Inappropriate Prescribing to the Elderly: Comparison of new Protocol to Beers Criteria With Relation to Hospitalizations for ADRs. European Journal of Clinical Pharmacology [Internet]. 2014. [pristupljeno 11.12.2024.];70(4):483-490. doi: 10.1007/s00228-014-1648-3

S. Mimica Matanović i V. Vlahović Palčevski, "Potentially Inappropriate Prescribing to the Elderly: Comparison of new Protocol to Beers Criteria With Relation to Hospitalizations for ADRs", European Journal of Clinical Pharmacology, vol. 70, br. 4, str. 483-490, 2014. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:239:912433. [Citirano: 11.12.2024.]

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Podaci o radu
Naslov (engleski)Potentially Inappropriate Prescribing to the Elderly: Comparison of new Protocol to Beers Criteria With Relation to Hospitalizations for ADRs
AutorSuzana Mimica Matanović
MBZ: 292855
AutorVera Vlahović-Palčevski
MBZ: 194575
Autorova ustanova(Klinički bolnički centar Osijek)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Farmakologija
Sažetak (engleski)
Screening tools for detecting potentially inappropriate medications (PIMs) represent an important way to assess drug prescribing in the elderly. Recently, we introduced a new comprehensive tool to detect both PIMs and clinically important drug-drug interactions (DDI). The aim of the study was to assess the applicability of the new tool.The new tool was used to detect PIMs and DDI and to assess their relation to morbidity and hospital admissions. It was also compared to the widely used Beers criteria. The study population included 454 consecutive patients aged ≥65 years who were acutely admitted to the Department of Internal Medicine of the University Hospital of Osijek. The Naranjo protocol was used to analyze the causal relationship between a drug and an adverse event.According to the new protocol, 44 % patients were taking PIMs, while 33 % patients were taking drugs with potentially serious DDIs. In 11 % of the overall number of patients, the cause of admission was adverse drug reaction (ADR), and among contributing drugs, 44 % were potentially inappropriate according to our protocol. Gastrointestinal bleeding was the most common diagnosis causing ADR-associated admission, and in 72 % cases, either PIM or a potentially serious DDI was involved.The new Croatian tool detected a high number of patients taking PIMs and/or having potentially important drug-drug interactions. The tool also detected almost half of the drugs contributing to ADR-associated admission. We expect the tool to be useful in prescription evaluation for the elderly inpatient and outpatient population.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaEuropean Journal of Clinical Pharmacology
Brojčani podacivol. 70, br. 4, str. 483-490
p-ISSN0031-6970
e-ISSN1432-1041
DOIhttps://doi.org/10.1007/s00228-014-1648-3
URN:NBNurn:nbn:hr:239:912433
Datum objave publikacije2014
URL dokumentahttps://europepmc.org/article/med/24458542
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2020-05-22 08:04:40