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Auxiliary Diagnostic Potential of Ventricle Geometry and late Gadolinium Enhancement in left Ventricular Non-compaction; Non-randomized case Control Study
BMC Cardiovascular Disorders, 17 (2017), 1; 2-9. https://doi.org/10.1186/s12872-017-0721-0
Boban, Marko; Peša, Vladimir; Gabrić, Ivo Darko; Manola, Šime; Peršić, Viktor; Antić-Kauzlarić, Helena; Žulj, Marinko; Včev, Aleksandar

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Boban, M., Peša, V., Gabrić, I. D., Manola, Š., Peršić, V., Antić Kauzlarić, H. ... Včev, A. (2017). Auxiliary Diagnostic Potential of Ventricle Geometry and late Gadolinium Enhancement in left Ventricular Non-compaction; Non-randomized case Control Study. BMC Cardiovascular Disorders, 17. (1), 2-9. doi: 10.1186/s12872-017-0721-0

Boban, Marko, et al. "Auxiliary Diagnostic Potential of Ventricle Geometry and late Gadolinium Enhancement in left Ventricular Non-compaction; Non-randomized case Control Study." BMC Cardiovascular Disorders, vol. 17, br. 1, 2017, str. 2-9. https://doi.org/10.1186/s12872-017-0721-0

Boban, Marko, Vladimir Peša, Ivo Darko Gabrić, Šime Manola, Viktor Peršić, Helena Antić Kauzlarić, Marinko Žulj i Aleksandar Včev. "Auxiliary Diagnostic Potential of Ventricle Geometry and late Gadolinium Enhancement in left Ventricular Non-compaction; Non-randomized case Control Study." BMC Cardiovascular Disorders 17, br. 1 (2017): 2-9. https://doi.org/10.1186/s12872-017-0721-0

Boban, M., et al. (2017) 'Auxiliary Diagnostic Potential of Ventricle Geometry and late Gadolinium Enhancement in left Ventricular Non-compaction; Non-randomized case Control Study', BMC Cardiovascular Disorders, 17(1), str. 2-9. doi: 10.1186/s12872-017-0721-0

Boban M, Peša V, Gabrić ID, Manola Š, Peršić V, Antić Kauzlarić H, i sur.. Auxiliary Diagnostic Potential of Ventricle Geometry and late Gadolinium Enhancement in left Ventricular Non-compaction; Non-randomized case Control Study. BMC Cardiovascular Disorders [Internet]. 2017. [pristupljeno 30.03.2024.];17(1):2-9. doi: 10.1186/s12872-017-0721-0

M. Boban, et al., "Auxiliary Diagnostic Potential of Ventricle Geometry and late Gadolinium Enhancement in left Ventricular Non-compaction; Non-randomized case Control Study", BMC Cardiovascular Disorders, vol. 17, br. 1, str. 2-9, 2017. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:239:159247. [Citirano: 30.03.2024.]

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Podaci o radu
Naslov (engleski)Auxiliary Diagnostic Potential of Ventricle Geometry and late Gadolinium Enhancement in left Ventricular Non-compaction; Non-randomized case Control Study
AutorMarko Boban
MBZ: 340711
AutorVladimir Peša
AutorIvo Darko Gabrić
MBZ: 352036
AutorŠime Manola
MBZ: 284123
AutorViktor Peršić
MBZ: 303361
AutorHelena Antić-Kauzlarić
AutorMarinko Žulj
AutorAleksandar Včev
MBZ: 141721
Autorova ustanovaSveučilište u Rijeci
Autorova ustanova(Klinički bolnički centar Osijek)
Autorova ustanovaSveučilište Josipa Jurja Strossmayera u Osijeku
Medicinski fakultet Osijek
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background: There are still ambiguities existing in regard to left ventricular non-compaction (LVNC) diagnostic imaging. The aim of our study was to analyze diagnostic potential of late gadolinium enhancement (LGE) and ventricle geometry in patients with LVNC and controls. Methods: Data on cardiac magnetic resonance imaging (CMR) studies for LVNC were reassessed from the hospital’s database (3.75 years; n=1975 exams). Matching sample of controls included cases with no structural heart disease, hypertrophic or dilative cardiomyopathy, arrhythmogenic right ventricular dysplasia or subacute myocarditis. Eccentricity of the left ventricle was measured at end diastole in the region with pronounced NC and maximal to minimal ratio (MaxMinEDDR) was calculated. Results: Study included 255 patients referred for CMR, 100 (39.2%) with LVNC (prevalence in the studied period 5.01%) and 155 (60.8%) controls. Existing LGE had sensitivity of 52.5% (95%-CI:42.3–62.5), specificity of 80.4% (95%-CI:73.2–86.5) for LVNC, area under curve (AUC) 0.664 (95%-CI:0.603–0.722);p<0.001. MaxMinEDDR>1.10 had sensitivity of 95.0% (95%- CI:88.7–98.4), specificity of 82.6% (95%-CI: 75.7–88.2) for LVNC, AUC 0.917 (95%-CI:0.876–0.948); p<0.001. LGE correlated with Max-Min-EDD-R (Rho=0.130; p=0.038) and there was significant difference in ROC analysis ΔAUC0.244 (95%-CI:0. 175–0.314); p<0.001. LGE also correlated negatively with stroke volume and systolic function (both p<0.05, respectively). Conclusions: LGE was found to be frequently expressed in patients with LVNC, but without sufficient power to be used as a discriminative diagnostic parameter. Both LGE and eccentricity of the left ventricle were found to be relatively solid diagnostic landmarks of complex infrastructural and functional changes within the failing heart.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBMC Cardiovascular Disorders
Brojčani podacivol. 17, br. 1, str. 2-9
e-ISSN1471-2261
DOIhttps://doi.org/10.1186/s12872-017-0721-0
URN:NBNurn:nbn:hr:239:159247
Datum objave publikacije2017
URL dokumentahttps://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-017-0721-0
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2019-10-23 11:00:36