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Models of Drug Induced Liver Injury (DILI) - Current Issues and Future Perspectives
Current Drug Metabolism, 19 (2018), 10; 830-838. https://doi.org/10.2174/1389200219666180523095355
Kuna, Lucija; Božić, Ivana; Kizivat, Tomislav; Bojanić, Kristina; Mršo, Margareta; Kralj, Edgar; Smolić, Robert; Wue, George Y.; Smolić, Martina

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Kuna, L., Božić, I., Kizivat, T., Bojanić, K., Mršo, M., Kralj, E. ... Smolić, M. (2018). Models of Drug Induced Liver Injury (DILI) - Current Issues and Future Perspectives. Current Drug Metabolism, 19. (10), 830-838. doi: 10.2174/1389200219666180523095355

Kuna, Lucija, et al. "Models of Drug Induced Liver Injury (DILI) - Current Issues and Future Perspectives." Current Drug Metabolism, vol. 19, br. 10, 2018, str. 830-838. https://doi.org/10.2174/1389200219666180523095355

Kuna, Lucija, Ivana Božić, Tomislav Kizivat, Kristina Bojanić, Margareta Mršo, Edgar Kralj, Robert Smolić, George Y. Wue i Martina Smolić. "Models of Drug Induced Liver Injury (DILI) - Current Issues and Future Perspectives." Current Drug Metabolism 19, br. 10 (2018): 830-838. https://doi.org/10.2174/1389200219666180523095355

Kuna, L., et al. (2018) 'Models of Drug Induced Liver Injury (DILI) - Current Issues and Future Perspectives', Current Drug Metabolism, 19(10), str. 830-838. doi: 10.2174/1389200219666180523095355

Kuna L, Božić I, Kizivat T, Bojanić K, Mršo M, Kralj E, i sur.. Models of Drug Induced Liver Injury (DILI) - Current Issues and Future Perspectives. Current Drug Metabolism [Internet]. 2018. [pristupljeno 26.10.2024.];19(10):830-838. doi: 10.2174/1389200219666180523095355

L. Kuna, et al., "Models of Drug Induced Liver Injury (DILI) - Current Issues and Future Perspectives", Current Drug Metabolism, vol. 19, br. 10, str. 830-838, 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:239:919465. [Citirano: 26.10.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:239:919465
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Podaci o radu
Naslov (engleski)Models of Drug Induced Liver Injury (DILI) - Current Issues and Future Perspectives
AutorLucija Kuna
MBZ: 353546
AutorIvana Božić
AutorTomislav Kizivat
AutorKristina Bojanić
MBZ: 272625
AutorMargareta Mršo
AutorEdgar Kralj
AutorRobert Smolić
MBZ: 292166
AutorGeorge Y. Wue
AutorMartina Smolić
MBZ: 292155
Autorova ustanova(Klinički bolnički centar Osijek)
Autorova ustanovaSveučilište Josipa Jurja Strossmayera u Osijeku
Medicinski fakultet Osijek
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Farmacija
Farmacija
Sažetak (engleski)
BACKGROUND: Drug-induced Liver Injury (DILI) is an important cause of acute liver failure cases in the United States, and remains a common cause of withdrawal of drugs in both preclinical and clinical phases. METHODS: A structured search of bibliographic databases - Web of Science Core Collection, Scopus and Medline for peer-reviewed articles on models of DILI was performed. The reference lists of relevant studies was prepared and a citation search for the included studies was carried out. In addition, the characteristics of screened studies were described. RESULTS: One hundred and six articles about the existing knowledge of appropriate models to study DILI in vitro and in vivo with special focus on hepatic cell models, variations of 3D co-cultures, animal models, databases and predictive modeling and translational biomarkers developed to understand the mechanisms and pathophysiology of DILI are described. CONCLUSION: Besides descriptions of current applications of existing modeling systems, associated advantages and limitations of each modeling system and future directions for research development are discussed as well.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCurrent Drug Metabolism
Brojčani podacivol. 19, br. 10, str. 830-838
p-ISSN1389-2002
DOIhttps://doi.org/10.2174/1389200219666180523095355
URN:NBNurn:nbn:hr:239:919465
Datum objave publikacije2018
URL dokumentahttp://www.eurekaselect.com/162371/article
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2019-10-29 11:39:40