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Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers
COPD: Journal of Chronic Obstructive Pulmonary Disease, 13 (2016), 6; 741-749. https://doi.org/10.3109/15412555.2016.1164129
Labor, Marina; Vrbica, Žarko; Gudelj, Ivan; Labor, Slavica; Jurić, Iva; Plavec, Davor

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Labor, M., Vrbica, Ž., Gudelj, I., Labor, S., Jurić, I. i Plavec, D. (2016). Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers. COPD: Journal of Chronic Obstructive Pulmonary Disease, 13. (6), 741-749. doi: 10.3109/15412555.2016.1164129

Labor, Marina, et al. "Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers." COPD: Journal of Chronic Obstructive Pulmonary Disease, vol. 13, br. 6, 2016, str. 741-749. https://doi.org/10.3109/15412555.2016.1164129

Labor, Marina, Žarko Vrbica, Ivan Gudelj, Slavica Labor, Iva Jurić i Davor Plavec. "Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers." COPD: Journal of Chronic Obstructive Pulmonary Disease 13, br. 6 (2016): 741-749. https://doi.org/10.3109/15412555.2016.1164129

Labor, M., et al. (2016) 'Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers', COPD: Journal of Chronic Obstructive Pulmonary Disease, 13(6), str. 741-749. doi: 10.3109/15412555.2016.1164129

Labor M, Vrbica Ž, Gudelj I, Labor S, Jurić I, Plavec D. Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers. COPD: Journal of Chronic Obstructive Pulmonary Disease [Internet]. 2016. [pristupljeno 08.12.2024.];13(6):741-749. doi: 10.3109/15412555.2016.1164129

M. Labor, Ž. Vrbica, I. Gudelj, S. Labor, I. Jurić i D. Plavec, "Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers", COPD: Journal of Chronic Obstructive Pulmonary Disease, vol. 13, br. 6, str. 741-749, 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:239:141036. [Citirano: 08.12.2024.]

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Podaci o radu
Naslov (engleski)Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers
AutorMarina Labor
MBZ: 357633
AutorŽarko Vrbica
MBZ: 259013
AutorIvan Gudelj
AutorSlavica Labor
MBZ: 330076
AutorIva Jurić
AutorDavor Plavec
MBZ: 159962
Autorova ustanovaSveučilište u Dubrovniku
Autorova ustanova(Klinički bolnički centar Osijek)
Autorova ustanovaSveučilište Josipa Jurja Strossmayera u Osijeku
Medicinski fakultet Osijek
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Although only less than one-third of smokers develop COPD, early marker(s) of COPD development are lacking. The aim of this research was to assess the ability of an average equilibrium exhaled breath temperature (EBT) in identifying susceptibility to cigarette smoke so as to predict COPD development in smokers at risk. The study was a part of a multicenter prospective cohort study in current smokers (N = 140, both sexes, 40-65 years, ≥20 pack-years) with no prior diagnosis of COPD. Diagnostic workup includes history, physical, quality of life, hematology and highly sensitive CRP, EBT before and after smoking a cigarette, lung function with bronchodilator test, and 6-minute walk test. Patients without a diagnosis of COPD and in GOLD 1 stage at initial assessment were reassessed after 2 years. COPD was additionally diagnosed based on lower level of normal (LLN) lung function criteria. Utility of EBT for disease progression was analyzed using receiver operator curve (ROC) and logistic regression analyses. Change in EBT after smoking a cigarette at initial visit (ΔEBT) was significantly predictive for disease progression (newly diagnosed COPD; newly diagnosed COPD + severity progression) after 2 years (p < 0.05 for both). ΔEBT had an AUC of 0.859 (p = 0.011) with sensitivity of 66.7% and specificity of 98.1% for newly diagnosed COPD using LLN criteria. We conclude that EBT shows potential for predicting the future development of COPD in current smokers. This was best seen using LLN to diagnose COPD, adding further evidence to question the use of GOLD criteria for diagnosing COPD.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCOPD: Journal of Chronic Obstructive Pulmonary Disease
Brojčani podacivol. 13, br. 6, str. 741-749
p-ISSN1541-2555
e-ISSN1541-2563
DOIhttps://doi.org/10.3109/15412555.2016.1164129
URN:NBNurn:nbn:hr:239:141036
Datum objave publikacije2016
URL dokumentahttps://www.tandfonline.com/doi/full/10.3109/15412555.2016.1164129
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 3.0 (CC BY 3.0)
Datum i vrijeme pohrane2019-10-29 12:49:50