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Obesity Related Coronary Microvascular Dysfunction: from Basic to Clinical Practice
Cardiology Research and Practice, 2016 (2016); 1-7. https://doi.org/10.1155/2016/8173816
Selthofer-Relatić, Kristina; Bošnjak, I.; Kibel, Aleksandar

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Selthofer Relatić, K., Bošnjak, I. i Kibel, A. (2016). Obesity Related Coronary Microvascular Dysfunction: from Basic to Clinical Practice. Cardiology Research and Practice, 2016., 1-7. doi: 10.1155/2016/8173816

Selthofer Relatić, Kristina, et al. "Obesity Related Coronary Microvascular Dysfunction: from Basic to Clinical Practice." Cardiology Research and Practice, vol. 2016, 2016, str. 1-7. https://doi.org/10.1155/2016/8173816

Selthofer Relatić, Kristina, I. Bošnjak i Aleksandar Kibel. "Obesity Related Coronary Microvascular Dysfunction: from Basic to Clinical Practice." Cardiology Research and Practice 2016 (2016): 1-7. https://doi.org/10.1155/2016/8173816

Selthofer Relatić, K., Bošnjak, I. i Kibel, A. (2016) 'Obesity Related Coronary Microvascular Dysfunction: from Basic to Clinical Practice', Cardiology Research and Practice, 2016, str. 1-7. doi: 10.1155/2016/8173816

Selthofer Relatić K, Bošnjak I, Kibel A. Obesity Related Coronary Microvascular Dysfunction: from Basic to Clinical Practice. Cardiology Research and Practice [Internet]. 2016. [pristupljeno 10.12.2024.];2016:1-7. doi: 10.1155/2016/8173816

K. Selthofer Relatić, I. Bošnjak i A. Kibel, "Obesity Related Coronary Microvascular Dysfunction: from Basic to Clinical Practice", Cardiology Research and Practice, vol. 2016, str. 1-7, 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:239:214684. [Citirano: 10.12.2024.]

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Podaci o radu
Naslov (engleski)Obesity Related Coronary Microvascular Dysfunction: from Basic to Clinical Practice
AutorKristina Selthofer-Relatić
MBZ: 333024
AutorI. Bošnjak
AutorAleksandar Kibel
MBZ: 344370
Autorova ustanova(Klinički bolnički centar Osijek)
Autorova ustanovaSveučilište Josipa Jurja Strossmayera u Osijeku
Medicinski fakultet Osijek
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Obesity related coronary microvascular disease is a medical entity which is not yet fully elucidated. The pathophysiological basis of coronary microcirculatory dysfunction consists of a heterogeneous group of disorders with individual morphologic/functional/clinical presentation and prognosis. Coronary microcirculatory changes include mechanisms connected with vascular dysfunction, as well as extravascular and vasostructural changes in responses to neural, mechanical, and metabolic factors. Cardiometabolic changes that include obesity, dyslipidemia, diabetes mellitus type II, and hypertension are associated with atherosclerosis of epicardial coronary arteries and/or microvascular coronary dysfunction, with incompletely understood underlying mechanisms. In obesity, microvascular disease is mediated via adipokines/cytokines causing chronic, subclinical inflammation with (a) reduced NO-mediated dilatation, (b) changed endothelial- and smooth muscle-dependent vasoregulating mechanisms, (c) altered vasomotor control with increased sympathetic activity, and (d) obesity related hypertension with cardiomyocytes hypertrophy and impaired cardiac vascular adaptation to metabolic needs. From a clinical point of view it can present itself in acute or chronic form with different prognosis, as a practice problem for real-life diagnosis and treatment.
Jezikengleski
Vrsta publikacijeStručni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCardiology Research and Practice
Brojčani podacivol. 2016, str. 1-7
p-ISSN2090-8016
e-ISSN2090-0597
DOIhttps://doi.org/10.1155/2016/8173816
URN:NBNurn:nbn:hr:239:214684
Datum objave publikacije2016
URL dokumentahttps://www.hindawi.com/journals/crp/2016/8173816/
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2019-12-03 07:53:40