prikaz prve stranice dokumenta Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: a Comparative Study
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Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: a Comparative Study
Mediators of Inflammation, 2019 (2019); 1-18. https://doi.org/10.1155/2019/6715275
Mihalj, Martina; Matić, Anita; Mihaljević, Zrinka; Barić, Lidija; Stupin, Ana; Drenjančević, Ines

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Mihalj, M., Matić, A., Mihaljević, Z., Barić, L., Stupin, A. i Drenjančević, I. (2019). Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: a Comparative Study. Mediators of Inflammation, 2019., 1-18. doi: 10.1155/2019/6715275

Mihalj, Martina, et al. "Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: a Comparative Study." Mediators of Inflammation, vol. 2019, 2019, str. 1-18. https://doi.org/10.1155/2019/6715275

Mihalj, Martina, Anita Matić, Zrinka Mihaljević, Lidija Barić, Ana Stupin i Ines Drenjančević. "Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: a Comparative Study." Mediators of Inflammation 2019 (2019): 1-18. https://doi.org/10.1155/2019/6715275

Mihalj, M., et al. (2019) 'Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: a Comparative Study', Mediators of Inflammation, 2019, str. 1-18. doi: 10.1155/2019/6715275

Mihalj M, Matić A, Mihaljević Z, Barić L, Stupin A, Drenjančević I. Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: a Comparative Study. Mediators of Inflammation [Internet]. 2019. [pristupljeno 08.12.2024.];2019:1-18. doi: 10.1155/2019/6715275

M. Mihalj, A. Matić, Z. Mihaljević, L. Barić, A. Stupin i I. Drenjančević, "Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: a Comparative Study", Mediators of Inflammation, vol. 2019, str. 1-18, 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:239:810271. [Citirano: 08.12.2024.]

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Podaci o radu
Naslov (engleski)Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: a Comparative Study
AutorMartina Mihalj
MBZ: 322792
AutorAnita Matić
MBZ: 326344
AutorZrinka Mihaljević
MBZ: 324952
AutorLidija Barić
AutorAna Stupin
MBZ: 322935
AutorInes Drenjančević
MBZ: 209603
Autorova ustanova(Klinički bolnički centar Osijek)
Autorova ustanovaSveučilište Josipa Jurja Strossmayera u Osijeku
Medicinski fakultet Osijek
Znanstveno / umjetničko
područje, polje i grana		BIOTEHNIČKE ZNANOSTI
Nutricionizam
Dijetoterapija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Klinička imunologija
Sažetak (engleski)
This study is aimed at assessing the effects of a short-term high-salt (HS) diet on the peripheral blood leukocyte (PBL) activation status in healthy rats and young human individuals. Distribution of PBL subpopulations and surface expression of integrins were determined using flow cytometry in 36 men and women on a 7-day low-salt diet (<3.2 g salt/day) immediately followed by a 7-day HS diet (~14 g salt/day) or in Sprague-Dawley (SD) rats (n = 24) on a 0.4% NaCl diet (aLS group) or a 4% NaCl diet (aHS group) for 7 days. The aHS group presented with an increased frequency of granulocytes, while the frequency of lymphocytes was reduced. Although in humans HS diet reduced the expression of CD11b(act) integrin on lymphocytes, the frequency of CD11b(act)-bearing cells among all PBL subsets was increased. The aHS group of rats exhibited increased expression of total CD11b/c in granulocytes and CD3 lymphocytes. The expression of CD11a was significantly reduced in all PBL subsets from human subjects and increased in the aHS group. CD49d expression on all PBL subsets was significantly decreased in both humans and rats. In human subjects, we found reduced frequencies of intermediate monocytes accompanied by a reciprocal increase in classical monocytes. Present results suggest that a short-term HS diet can alter leukocytes' activation status and promote vascular low-grade inflammation.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaMediators of Inflammation
Brojčani podacivol. 2019, str. 1-18
p-ISSN0962-9351
e-ISSN1466-1861
DOIhttps://doi.org/10.1155/2019/6715275
URN:NBNurn:nbn:hr:239:810271
Datum objave publikacije2019
URL dokumentahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766117/
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2020-01-17 13:33:35