prikaz prve stranice dokumenta Red Blood Cell Distribution Width as a Simple Negative Prognostic Factor in Patients With Diffuse Large B-cell Lymphoma: a Retrospective Study
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Red Blood Cell Distribution Width as a Simple Negative Prognostic Factor in Patients With Diffuse Large B-cell Lymphoma: a Retrospective Study
Croatian medical journal, 56 (2015), 4; 334-343. https://doi.org/10.3325/cmj.2015.56.334
Perisa, Vlatka; Zibar, Lada; Sincic-Petricevic, Jasminka; Knezovic, Ana; Perisa, Igor; Barbic, Jerko

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Perisa, V., Zibar, L., Sincic Petricevic, J., Knezovic, A., Perisa, I. i Barbic, J. (2015). Red Blood Cell Distribution Width as a Simple Negative Prognostic Factor in Patients With Diffuse Large B-cell Lymphoma: a Retrospective Study. Croatian medical journal, 56. (4), 334-343. doi: 10.3325/cmj.2015.56.334

Perisa, Vlatka, et al. "Red Blood Cell Distribution Width as a Simple Negative Prognostic Factor in Patients With Diffuse Large B-cell Lymphoma: a Retrospective Study." Croatian medical journal, vol. 56, br. 4, 2015, str. 334-343. https://doi.org/10.3325/cmj.2015.56.334

Perisa, Vlatka, Lada Zibar, Jasminka Sincic Petricevic, Ana Knezovic, Igor Perisa i Jerko Barbic. "Red Blood Cell Distribution Width as a Simple Negative Prognostic Factor in Patients With Diffuse Large B-cell Lymphoma: a Retrospective Study." Croatian medical journal 56, br. 4 (2015): 334-343. https://doi.org/10.3325/cmj.2015.56.334

Perisa, V., et al. (2015) 'Red Blood Cell Distribution Width as a Simple Negative Prognostic Factor in Patients With Diffuse Large B-cell Lymphoma: a Retrospective Study', Croatian medical journal, 56(4), str. 334-343. doi: 10.3325/cmj.2015.56.334

Perisa V, Zibar L, Sincic Petricevic J, Knezovic A, Perisa I, Barbic J. Red Blood Cell Distribution Width as a Simple Negative Prognostic Factor in Patients With Diffuse Large B-cell Lymphoma: a Retrospective Study. Croatian medical journal [Internet]. 2015. [pristupljeno 17.11.2024.];56(4):334-343. doi: 10.3325/cmj.2015.56.334

V. Perisa, L. Zibar, J. Sincic Petricevic, A. Knezovic, I. Perisa i J. Barbic, "Red Blood Cell Distribution Width as a Simple Negative Prognostic Factor in Patients With Diffuse Large B-cell Lymphoma: a Retrospective Study", Croatian medical journal, vol. 56, br. 4, str. 334-343, 2015. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:239:474625. [Citirano: 17.11.2024.]

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Podaci o radu
Naslov (engleski)Red Blood Cell Distribution Width as a Simple Negative Prognostic Factor in Patients With Diffuse Large B-cell Lymphoma: a Retrospective Study
AutorVlatka Perisa
MBZ: 363604
AutorLada Zibar
MBZ: 254864
AutorJasminka Sincic-Petricevic
AutorAna Knezovic
MBZ: 320641
AutorIgor Perisa
AutorJerko Barbic
MBZ: 258420
Autorova ustanova(Klinički bolnički centar Osijek)
Autorova ustanovaSveučilište Josipa Jurja Strossmayera u Osijeku
Medicinski fakultet Osijek
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Onkologija
Sažetak (engleski)
Aim to determine the prognostic value of baseline red blood cell distribution width (RDW) in diffuse large B cell lymphoma (DLBCL) patients. Methods: data from 81 DLBCL patients diagnosed from 2006 to 2013 at the University Hospital Center Osijek, Osijek, Croatia, were reviewed. We evaluated disease outcome, overall survival (OS) and event-free survival (EFS), an demographic, clinical and laboratory factors affecting outcome. Univariate analysis and Cox regression analysis were used. Results: median age of patients was 64 years, 29 were men (35.8%). Higher RDW levels (%) were found in patients with advanced Ann Arbor clinical stage (14.94 ± 1.82 vs 13.55 ± 1.54, P = 0.001) and in those with poor response to therapy (14.94 ± 1.82 vs 13.55 ± 1.54, P = 0.001). Patients with RDW>15% (cut-off was calculated by receiver operating characteristics) had significantly worse OS (median [range], 33 months [20-46] vs 74 months [65-82], P < 0.001) and EFS (27 months [15-40] vs 68 months [59-77], P < 0.001). Cox regression analysis showed that RDW>15% was an independent prognostic factor for OS (HR 3.654, 95% CI 1.128-11.836) and EFS (HR 2.611, 95% CI 1.012-6-739). Conclusion: high baseline RDW is an independent prognostic marker of poor outcome in patients with DLBCL. RDW could be an easily available and inexpensive marker for the risk stratification in patients with DLBCL.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatian medical journal
Brojčani podacivol. 56, br. 4, str. 334-343
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2015.56.334
URN:NBNurn:nbn:hr:239:474625
Datum objave publikacije2015
URL dokumentahttps://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=222900
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2019-09-16 12:25:31