prikaz prve stranice dokumenta Cultured Circulating Tumor Cells and Their Derived Xenografts for Personalized Oncology
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Cultured Circulating Tumor Cells and Their Derived Xenografts for Personalized Oncology
Asian Journal of Urology, 3 (2016), 4; 240-253. https://doi.org/10.1016/j.ajur.2016.08.005
Wang, Ruoxiang; Chu, Chia-Yi; Mrđenović, Stefan; Annamalai, Alagappan A.; Hendifar, Andrew E.; Nissen, Nicholas N.; Tomlinson, James S.; Lewis, Michael; Palanisamy, Nallasivam; Tseng, Hsian-Rong; Posadas, Edwin M.; Stephen J., Pandol; Zhau, Haiyen E.; Chung, Leland W.K.

Citirajte ovaj rad

Wang, R., Chu, C. Y., Mrđenović, S., Annamalai, A. A., Hendifar, A. E., Nissen, N. N. ... Chung, L. W. (2016). Cultured Circulating Tumor Cells and Their Derived Xenografts for Personalized Oncology. Asian Journal of Urology, 3. (4), 240-253. doi: 10.1016/j.ajur.2016.08.005

Wang, Ruoxiang, et al. "Cultured Circulating Tumor Cells and Their Derived Xenografts for Personalized Oncology." Asian Journal of Urology, vol. 3, br. 4, 2016, str. 240-253. https://doi.org/10.1016/j.ajur.2016.08.005

Wang, Ruoxiang, Chia Yi Chu, Stefan Mrđenović, Alagappan A. Annamalai, Andrew E. Hendifar, Nicholas N. Nissen, James S. Tomlinson, et al. "Cultured Circulating Tumor Cells and Their Derived Xenografts for Personalized Oncology." Asian Journal of Urology 3, br. 4 (2016): 240-253. https://doi.org/10.1016/j.ajur.2016.08.005

Wang, R., et al. (2016) 'Cultured Circulating Tumor Cells and Their Derived Xenografts for Personalized Oncology', Asian Journal of Urology, 3(4), str. 240-253. doi: 10.1016/j.ajur.2016.08.005

Wang R, Chu CY, Mrđenović S, Annamalai AA, Hendifar AE, Nissen NN, i sur.. Cultured Circulating Tumor Cells and Their Derived Xenografts for Personalized Oncology. Asian Journal of Urology [Internet]. 2016. [pristupljeno 10.12.2024.];3(4):240-253. doi: 10.1016/j.ajur.2016.08.005

R. Wang, et al., "Cultured Circulating Tumor Cells and Their Derived Xenografts for Personalized Oncology", Asian Journal of Urology, vol. 3, br. 4, str. 240-253, 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:239:568078. [Citirano: 10.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:239:568078
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Naslov (engleski)Cultured Circulating Tumor Cells and Their Derived Xenografts for Personalized Oncology
AutorRuoxiang Wang
AutorChia-Yi Chu
AutorStefan Mrđenović
MBZ: 103524
AutorAlagappan A. Annamalai
AutorAndrew E. Hendifar
AutorNicholas N. Nissen
AutorJames S. Tomlinson
AutorMichael Lewis
AutorNallasivam Palanisamy
AutorHsian-Rong Tseng
AutorEdwin M. Posadas
AutorPandol Stephen J.
AutorHaiyen E. Zhau
AutorLeland W.K. Chung
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Onkologija
Sažetak (engleski)
Recent cancer research has demonstrated the existence of circulating tumor cells (CTCs) in cancer patient's blood. Once identified, CTC biomarkers will be invaluable tools for clinical diagnosis, prognosis and treatment. In this review, we propose ex vivo culture as a rational strategy for large scale amplification of the limited numbers of CTCs from a patient sample, to derive enough CTCs for accurate and reproducible characterization of the biophysical, biochemical, gene expressional and behavioral properties of the harvested cells. Because of tumor cell heterogeneity, it is important to amplify all the CTCs in a blood sample for a comprehensive understanding of their role in cancer metastasis. By analyzing critical steps and technical issues in ex vivo CTC culture, we developed a cost-effective and reproducible protocol directly culturing whole peripheral blood mononuclear cells, relying on an assumed survival advantage in CTCs and CTC-like cells over the normal cells to amplify this specified cluster of cancer cells.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaAsian Journal of Urology
Brojčani podacivol. 3, br. 4, str. 240-253
p-ISSN2214-3882
e-ISSN2214-3890
DOIhttps://doi.org/10.1016/j.ajur.2016.08.005
URN:NBNurn:nbn:hr:239:568078
Datum objave publikacije2016
URL dokumentahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730836/
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2019-11-08 11:56:06